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Biology

Cell Division: Mitosis and Meiosis

Feature Mitosis Meiosis
Cell somatic sex (germ)
Division 1 2
Result 2 (2n) 4 (n)
Crossing over no yes

Mitosis

Division of somatic cells. As a result, 2 diploid cells identical to the parent cell are formed.

Phases:

  • Prophase: chromosomes condense (spiralize).
  • Metaphase: chromosomes line up at the equator.
  • Anaphase: chromatids move to the poles.
  • Telophase: nuclei form.

Interphase includes the G₁, S (DNA doubles) and G₂ periods.

Meiosis

Formation of gametes. Two successive divisions produce 4 haploid cells.

  • Meiosis I: reductional (homologous chromosomes separate).
  • Meiosis II: equational (chromatids separate).

Key facts

  • In humans, mitosis produces 46 chromosomes from 46, and meiosis produces 23 from 46.
  • Conjugation and crossing over occur in prophase of meiosis I. They ensure genetic diversity.
  • Significance of mitosis: growth, regeneration, asexual reproduction. Significance of meiosis: formation of gametes and spores.
  • In anaphase of mitosis, the number of chromosomes temporarily doubles (4n4c), because the chromatids become independent chromosomes.
  • DNA reduplication occurs in the S period (replication).